Archive for the ‘Fever’ Category

Cytokines That Induce Fever & Include Interleukin

Monday, January 18th, 2010

Endogenous pyrogens

  • The endogenous pyrogens are cytokines that induce fever and include interleukin-1 (IL-1), IL-6, IL-8, macrophage-inflammatory protein-1 (MIP-1), and interferon-g (IFN-g )
  • Polypeptides produced by a variety of hosperdero cells such as monocytes or macrophages, neoplastic cells that explain the existence of fever in malignancies.

The endogenous pyrogens converge to a brain region that regulates the fever, the preoptic area (POA) of the anterior hypothalamus. Mechanism controversy as endogenous pyrogens have to cross the blood brain barrier (BBB) which is impermeable to them. At least two routes are evident  : Active transport across the BBB by carrier-specific cytokines.

Message transfer where the BBB has fenestrations, ie sensory organs circumventriculares particularly in the organum vasculosum laminae terminalis (OVLT). But there are alternative routes: the circulation of cytokines induce the generation of prostaglandin E2 (PGE-2) and perhaps prostaglandins F2a (PGF-2a) permeable to the BBB, the most proximal putative mediator of fever, endothelial cells the cerebral microvasculature or perivascular macrophages and microglia and meningeal. Direct transmission to the POA of pyrogens messages via peripheral afferent (mostly vagal) activated by cytokines.

Tags: , , , , ,
Posted in Fever | No Comments »

Factors That Can Affect Body Temperature

Saturday, January 16th, 2010

Normal body temperature can change during any given day. It is usually higher at night. Other factors that can affect body temperature are:

  • In the second part of the menstrual cycle can elevate temperature by one degree or more.
  • Physical activity, strong emotion, eating, heavy clothing, medications, high temperature and high humidity can increase body temperature.

Fever is an important part of the body’s defenses against infection. Many infants and children develop high fevers with minor viral illnesses. While a fever for us a sign that a battle might be going in the body, the fever is fighting for the person and not against it.

Most bacteria and viruses that cause infections in people thrive best at 37 ° C (98.6 ° F).

Brain damage usually will not occur unless the fever is over 42 degrees C (107.6 ° F). The fever caused by untreated infection rarely exceeding 40.5 º C (105 ° F), unless the child is overdressed or trapped in a warm place.

Febrile seizures do occur in some children. However, most of them completed quickly, does not mean the child has epilepsy and cause no permanent damage.

Tags: , , ,
Posted in Fever | No Comments »

Description of Fever

Friday, January 15th, 2010

Fever

They will be 40 degrees or more. But for one are always 55. When it starts to shake and not cold. I look out the window to be sure, and everyone is in shirt. Cold does not, but I tremble like a leaf. And my feet are cold and boiling the head. I get out of bed and go to ibuprofen, walking very slowly, emulating a 98-year old, fucked and covered with flies, dragging his feet in slippers winter, refusing to feel the fever. So I will not have luck.

The tablet of ibuprofen is empty. But do not despair, because I can go buy another. But if I can walk to the bathroom, unless I can walk three blocks to the pharmacy. Still, going back to bed.

Ojala dream catch me and pass me the fever, even a little, to get out into the street. I start to scratch a pimple on my left arm, a little below the shoulder, arm in that part of the leftover meat. I find it easy, because I have quite long nails, like a guitarist. I scratch and I feel no pain, not even bothering me. I went out the pus that was enough, while if the stock was trading pus, I would make a few bucks. I keep scratching while watching the news on TV, dead people everywhere, especially in the ditches. I scratch and I scratch until blood begins to flow in my arm, but with the fever-hot body I did not realize. He trembled so. And on TV, a star old advised me to keep my jewelry in a safe place, assuming I had jewelry in my house, and saying that my house is unsafe. I laughed at the nerves. And I was scratching.

Tags: , , ,
Posted in Fever | No Comments »

Fever in Children

Thursday, January 14th, 2010

Fever in children is a symptom that worries parents too well and should be identified to adequately address the origin

A symptom of disease of great concern to parents, is fever, and is only touching the face, neck or stomach of our son or daughter, we realize that are warmer than normal. But not enough to know what they are warmer than normal, it is important to check the thermometer through how high is the fever, because it depends on immediate care and prevention of further damage, because if the thermometer hits more than 38 °, it will be necessary to take the child with your pediatrician to identify either the source of the fever and give appropriate treatment to control the disease that is causing.

Fever is not a disease but a symptom of many, usually of infectious or inflammatory, caused by some external agent, poisoning, allergies, rheumatic problems, neurological disorders and malignant tumors and certain mental processes. It is believed that fever is a reaction of self-defense, as the fever’s mission is to tire and reduce the enemy that may be a virus, bacterium, fungus, parasite or toxic substance active

Other manifestations that accompany fever are chills which, on trying to level the body temperature and acceleration of heart palpitations.

Although fever is very concerned and very disturbed, generally not dangerous to 39 °. Importantly, the body temperature is not the same in young children than in adults as in infants, the normal temperature is about 37 °, while in adults is 36 °. Usually newborns can not run a fever until 4 weeks old, because their system thermostat is not fully developed.

Also varies during the day, morning is usually lower than 5 ° at night, so when it comes to fever can reach 37.5 or 38 ° and is dangerous when it exceeds 41 degrees, as it can be put in life threatening or cause severe brain disorders. A temperature of 42 ° is tolerable only for a moment and causing severe brain damage and even death.

Tags: , , , , ,
Posted in Fever | No Comments »

What is meant by a fever?

Tuesday, January 12th, 2010

feverFever is an elevation of body temperature above normal. When a child has a fever, your body is responding to external aggression, usually an infection by viruses or bacteria.

Fever is thus a symptom or sign of alarm as a result of the body’s defense mechanism against something that is bothering. In short, high temperature is a primary barrier of the body to prevent the infection progress.

The normal temperature ranges from 36 º C to 37.5 C (degrees Celsius). For practical purposes it is considered a fever when the child’s temperature exceeds 37.5 ° C. when taken rectally

Mild fever or feverishness: from 37.0 C to 37.5 º C rectal or 38 axillary

Mild fever: from 37.5 C to 38.9 º C axillary

High fever: More than 38.9 º C axillary

(more…)

Tags: , , , , , , ,
Posted in Fever | No Comments »